Of the nine patients who underwent early surgery (≤8 weeks), two displayed a preoperative nystagmus whilst between 10 and 39 months post-operatively 8 (89%) exhibited a nystagmus. Fifteen of the 23 (65%) patients who experienced major form deprivation exhibited a nystagmus, of which 11 (73%) were manifest latent nystagmus (MLN). ![]() Visual acuity was assessed using forced-choice preferential looking techniques in the neonates and infants and with optotypes in the children. ![]() Eye alignment and fixation stability was measured using infrared recording systems and video. Twenty-three patients were considered to have cataracts, which were a major obstacle to vision (major form deprivation), 9 of whom underwent surgery within 8 weeks of birth (mean and SD = 5.2 ± 2.3 weeks) and 10 after 8 weeks (mean and SD = 33.9 ± 29.7 months). Thirty-three patients (aged 1 week to 12.8 years) with infantile cataracts (16 bilateral, 17 unilateral) were examined for periods up to 61 months. ![]() We wished to study how the severity and duration of early onset visual deprivation affects eye alignment and ocular stability.
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